What Is Herozyme®?

Herozyme® is an enzyme replacement therapy (ERT) used to treat people with MPS I

Herozyme® is a cost-effective biosimilar medicine indicated for the treatment of the non-neurological manifestations of MPS I in patients who lack, or have very low levels of, the enzyme α-L-iduronidase. Herozyme® contains laronidase, a lab-made form of the missing enzyme. By replacing this enzyme, Herozyme® helps the body break down and clear excess GAGs more effectively.

How Herozyme® Works

How to Take Herozyme®

Possible Side Effects

Herozyme® can cause side effects, some of which may occur during or shortly after the infusion, while others may appear later.

Common Side Effects

These are usually mild to moderate and may include:

Other side effects have been reported but occur less frequently.

Serious Reactions (Less Common)

These may include signs of a severe allergic reaction, such as:

• Difficulty breathing
• Sudden wheezing or tightness in the chest
• Swelling of the face, throat, or mouth

If any of these symptoms occur, seek medical help immediately.

Important Safety Information

Before receiving Herozyme®:

• Tell your healthcare provider about all medicines you take, including prescription, over-the-counter, and herbal products.
• Inform your doctor about any allergies or medical conditions you have.
• Herozyme® should not be used if you are allergic to laronidase or any of the ingredients in this medicine.
• If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your doctor before starting treatment.